姓名:陈必强
职称:教授
邮箱:chenbq@mail.buct.edu.cn
工作地点:科技大厦西配楼503 |
教育背景:
2001 学士,生物化工(北京化工大学)
2003 硕士,生物化工(北京化工大学)
2008 博士,生物化工(北京化工大学)
2006/01-2006/07 赴丹麦技术大学进行博士联合培养
2008.8-2010.6 博士后(清华大学化工系)
工作经历:
2010.8-2014.12,北京化工大学生命学院,副教授,硕士生导师
2015.1-2018.1,北京化工大学生命学院,见习教授,硕士生导师
2018.1-至今,北京化工大学生命学院,教授,博士生导师
学术兼职:
ljournal of molecular catalysis b: enzymatic,rsc advance, applied microbiology and biotechnology等国际期刊审稿人
主要研究领域:
长期从事生物催化剂工程的研究。作为项目负责人主持国家自然科学基金2项、国家973计划子课题2项、863计划子课题1项,企业横向课题2项。近年发表sci论文30多篇,申请专利11项(已授权6项,包括国际专利1项)。具体研究方向:
l新酶的筛选与酶的蛋白质工程改造
l酶的固定化微环境调控
l多酶催化体系构建
l新型酶反应器设计与酶反应过程在线监测、控制与系统集成
l生物催化新产品、新工艺开发
获奖及荣誉:
2008年“以脂肪酶为催化剂的化学品绿色合成工艺”获国家技术发明奖二等奖(第二完成人)
2005年“以脂肪酶为催化剂的绿色化学合成工艺”中国石化技术发明一等奖(第三完成人)
2010年获教育部“10000个科学难题”突出贡献奖
2011获年中国微生物学会酶工程专业委员会“青年优秀论文奖”
2013年入选北京市青年英才计划
2016年入选北京市科技新星计划
代表性著作:
selected publications:
1)cui c, chen h, chen b*, et al. genipin cross-linked glucose oxidase and catalase multi-enzyme for gluconic acid synthesis (2016). applied biochemistry and biotechnology, 1-10.
2)cui, c., nan, g., chen, x., chen, b*., & tan, t*. (2016). immobilization of yarrowia lipolytica, lipase ylip 2 for the bioicatalytic synthesis of phytosterol ester in a water activity controlled reactor. colloids & surfaces b biointerfaces, 146, 490-497.
3)cui, c., zhen, y., qu, j., chen, b*., & tan, t*. (2016). synthesis of biosafe isosorbide dicaprylate ester plasticizer by lipase in a solvent-free system and its sub-chronic toxicity in mice. rsc advances, 6(15), 11959-11966.
4)tao, y., dong, r., pavlidis, i. v., chen, b*., & tan, t. (2015). using imidazolium-based ionic liquids as dual solvent-catalysts for sustainable synthesis of vitamin esters: inspiration from bio- and organo-catalysis. green chemistry, 18(5), 1240-1248.
5)tao, y., chen, g., pavlidis, i. v., jiang, y., qie, l., & cui, c., liu l., chen, b*, & tan, t.* (2015). water-dependent kinetics guide complex lipase-mediated synthesis of biolubricants in a water activity control reactor. catalysis science & technology, 5(12), 5120-5128.
6)cui, c., tao, y., ge, c., zhen, y., chen, b*., & tan, t*. (2015). synergistic effects of amine and protein modified epoxy-support on immobilized lipase activity. colloids & surfaces b biointerfaces, 133(1), 51-57.
7)rong, x., cui, c., chen, b*., & tan, t. (2015). immobilizing yarrowia lipolytica, lipase lip2 via improvement of microspheres by gelatin modification. applied biochemistry & biotechnology, 177(3), 1-9.
8)cui, c., xie, r., tao, y., zeng, q., chen, b*, & tan t*. (2015). improving performance of yarrowia lipolytica, lipase lip2-catalyzed kinetic resolution of (r,s)-1-phenylethanol by solvent engineering. biocatalysis & biotransformation, 33(1), 38-43.
9)tao, y., cui, c., shen, h., luo, l., chen, b*., & tan, t*. (2014). enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. enzyme & microbial technology, 58-59(9), 60-67.
10)chen, biqiang,zhang, hong,cheong, ling-zhi,tan, tianwei,xu, xuebing ,enzymatic production of aba-type structured lipids containing omega-3 and medium-chain fatty acids: effects of different acyl donors on the acyl migration rate,food and bioprocess technology,2012,5(2):541-547
book chapters:
1)biqiang chen, yifeng tao, meng wang, di cai, tianwei tan: bioconversion of biomass to bulk chemicals. sustainable production of bulk chemicals, 01/2016; , isbn: 978-94-017-7473-4
2)陈必强,雷二庆、邢婉丽、刘冉、刘录祥、李奎、邱文德、李俊、刘洁,生物产业,《2017中国战略新兴产业发展报告》,中国工程科技发展战略研究院, 科学出版社, pp 124-146, 中国, 2016/11/10
教师寄语:
说真话
招生要求:
勤奋、开朗