姓名：冯嵬
职称：教授
邮箱：fengwei@mail.buct.edu.cn
办公地址：科技楼西602 |
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教育背景：
本科（1990）、硕士（1994）、博士（1998）北京化工大学化学工程专业
工作经历：
1999年-2000年：德国柏林工业大学
2001年-2004年：荷兰代尔夫特理工大学
2005年-今：北京化工大学生命科学与技术学院
主要研究领域：
通过基因工程技术改造酶，构建酶连续催化体系；内含子介导的蛋白质剪接；手性药物中间体的酶催化合成；酶固定。
科研项目：
作为负责人承担了国家自然科学基金项目、863项目和973课题项目
代表性著作：
1. yao chen, jinxin zou, jian sun, qiong qin, peijun ji, wei feng. by in-situ generation of hydroxyl radicals in concert with in-situ generation of o2. chemical engineering journal, 2022, 435, 134819.
2. jinxin zou, yao chen, wei feng. mechanism of dopa radical generation and transfer in metal-free class ie ribonucleotide reductase based on density functional theory. computational and structural biotechnology journal, 2022, 20, 1111–1131.
3. yining han, wenxin qu, wei feng. coupling a recombinant oxidase to catalase through specific noncovalent interaction to improve the oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid.enzyme and microbial technology, 2021, 150, 109895.
4. rong li, yao chen, kun du, wei feng. peptide bond formation between the hetrosubunits of ω-transaminase, alanine dehydrogenase, and formatedehydrogenase through subunit splicing promoted by heterodimerization of leucine zipper motifs. frontiers in bioengineering and biotechnology. 2020, 8, 686,1-13.
5. yao chen, hao chu, wei liu, wei feng. simultaneous synthesis of l-dopa and oxidation of d-amino acid by specific coupling of a peroxidase to d-amino acid oxidase. enzyme and microbial technology,2019,121, 8–16.
6. jian sun, yaqi fu, rong li, wei feng. multifunctional hollow−shell microspheres derived from cross-linking of mno2 nanoneedles by zirconium-based coordination polyme: enzyme mimicking, micromotors, and protein immobilization. chemistry of materials. 2018, 30, 1625−1634.
7. rong li, xiaoqi zhou, dan liu, wei feng. enhancing the activity and stability of mn-superoxide dismutase by one-by-one ligation to catalase.free radical biology and medicine, 2018, 129, 138-145.
8. kun du,jinjin zhao,jian sun, and wei feng. specific ligation of two multimeric enzymes with native peptides and immobilization with controlled molar ratio. bioconjugate chemistry. 2017, 28, 1166−1175..
9. jian sun, kun du, xiaoqiang song, qian gao, jingjing ma, wei feng. specific immobilization of d-amino acid oxidase mimicking multi-enzyme catalysis. green chemistry. 2015, 17, 4465–4472.
10. jian sun, kun du, li fu,jiang gao,haiyang zhang,wei feng. sodium hexadecyl sulfate as an interfacial substance adjusting the adsorption of a protein on carbon nanotubes. acs appl. mater. interfaces. 2014, 6, 15132− 15139.
11. kun du, jian sun,xiaoqiang song,huaming chen,wei feng, peijun ji. interaction of ionic liquid [bmin][cf3so3] with lysozyme investigated by two-dimensional fourier transform infrared spectroscopy. acs sustainable chemistry & engineering. 2014, 2, 1420−1428.
12. wei feng, peijun ji. enzymes immobilized on carbon nanotubes. biotechnology advances. 2011, 29, 889-895.
教师寄语:
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